The Random Present — Ketones for Cognition, Tim’s Greatest Lab Ends in 10+ Years, How Kevin Hit 100 Days Sober, Residence Protection, Vibe Coding Unleashed, and Extra (#822)

Welcome to a different wide-ranging “Random Present” episode I recorded with my shut pal Kevin Rose (digg.com)!

We cowl Kevin’s sobriety journey and marking 100 days with out alcohol, my outcomes with the ketogenic food plan and intermittent fasting, GLP-1 agonists, dwelling protection and safety, the way forward for Enterprise Capital, authenticating your self on-line, AI, the cultural shift towards human-to-human connection, Roblox, and extra.

Please get pleasure from!

Hearken to the episode on Apple Podcasts, Spotify, Overcast, Podcast Addict, Pocket Casts, Castbox, YouTube Music, Amazon Music, Audible, or in your favourite podcast platform. Watch the dialog on YouTube. The transcript of this episode could be discovered right here. Transcripts of all episodes could be discovered right here.

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Wish to hear the final time KevKev and I did one in all these Random Reveals? Hearken to our dialog right here through which we mentioned sustaining sobriety with a accomplice who nonetheless drinks, Taiwanese tea, discovering magic within the odd, the ups and downs of accelerated TMS, the intersection of AI and life sciences, deepfaked facet hustlers, when meditation retreats go proper (and incorrect), and far more.

SELECTED LINKS FROM THE EPISODE

Web site | Instagram | Twitter | Threads | Bluesky | Digg.com

The transcript of this episode could be discovered right here. Transcripts of all episodes could be discovered right here.

Folks

• Sigmund Freud: Austrian neurologist and founding father of psychoanalysis who revolutionized our understanding of the human psyche.
• Hokusai: Japanese ukiyo-e artist of the Edo interval, well-known for “The Nice Wave off Kanagawa” and influential woodblock prints.
• Craig Mod: Author, photographer, and writer identified for his considerate explorations of Japan, strolling, and digital publishing.
• Liam Neeson: Irish actor identified for dramatic roles in movies like Schindler’s Record and motion movies just like the Taken collection.
• Johnny Depp: American actor identified for eccentric characters together with Captain Jack Sparrow and Willy Wonka in Tim Burton’s adaptation.
• Gene Wilder: American actor and comic well-known for his iconic portrayal of Willy Wonka within the 1971 basic movie.
• Dr. Rhonda Patrick: PhD scientist and host of the FoundMyFitness podcast, specializing in diet, ageing, and well being optimization.
• Martin Berkhan: Health skilled and founding father of the Leangains intermittent fasting protocol that revolutionized versatile weight-reduction plan.
• Dr. Peter Attia: Doctor and longevity skilled specializing in the science of healthspan and lifespan optimization.
• Desmond Tutu: South African Anglican archbishop and Nobel Peace Prize winner famend for his anti-apartheid activism.
• Taran Butler: Aggressive shooter and founding father of Taran Tactical Improvements, identified for customized firearm modifications.
• Keanu Reeves: Canadian actor beloved for roles in The Matrix trilogy and the John Wick motion franchise.
• Jim Jefferies: Australian humorist and actor identified for his provocative and observational comedy fashion.
• Steven Seagal: American actor, screenwriter, and martial artist identified for motion movies within the Nineteen Eighties and Nineteen Nineties.
• Marc Andreessen: Co-founder of Andreessen Horowitz enterprise capital agency and co-creator of the Mosaic net browser.
• Josh Prepare dinner: Digital strategist and entrepreneur identified for his work in know-how and social media engagement.
• Sam Altman: CEO of OpenAI and outstanding determine in synthetic intelligence improvement and governance.
• Alexis Ohanian: Co-founder of Reddit and enterprise capitalist centered on early-stage know-how investments.
• Justin Mezzell: Digg CEO, designer, and artistic director identified for his distinctive illustration fashion and branding work.

Motion pictures, TV, and Media

• Shaun of the Lifeless: A 2004 British horror-comedy movie that brilliantly parodies zombie motion pictures whereas delivering real scares and laughs.
• Jason Bourne: An action-thriller movie collection following the amnesiac super-spy created by Robert Ludlum, starring Matt Damon.
• Snatch: A 2000 British crime-comedy movie by Man Ritchie that includes interconnected felony plots and memorable characters.
• Babe: A 1995 household comedy-drama a few pig who learns to herd sheep, combining live-action with groundbreaking animatronics.
• The Bare Gun: A comedy movie collection starring Leslie Nielsen because the bumbling Detective Frank Drebin, identified for its slapstick humor.
• Taken: An action-thriller movie collection starring Liam Neeson as a former CIA operative with “a really explicit set of expertise.”
• Willy Wonka & The Chocolate Manufacturing facility: A 1971 musical fantasy movie starring Gene Wilder because the eccentric chocolatier in Roald Dahl’s beloved story.
• John Wick: An motion movie collection starring Keanu Reeves as a legendary murderer searching for vengeance, identified for stylized battle choreography.
• Sluggish TV: A tv style that includes real-time, unedited protection of prolonged occasions like prepare journeys or knitting marathons.
• Playboy: An American males’s way of life and leisure journal based by Hugh Hefner in 1953.
• Wired: A month-to-month journal overlaying how rising applied sciences impression tradition, the economic system, and politics.

Books

• The 4-Hour Workweek by Timothy Ferriss: A step-by-step information to escaping the 9-5 grind via way of life design, automation, and the rules of working smarter quite than tougher.
• The 4-Hour Physique by Timothy Ferriss: An unusual information to fast fat-loss, unbelievable intercourse, and changing into superhuman via data-driven physique hacking and minimally efficient dose rules.
• The 4-Hour Chef by Timothy Ferriss: A meta-learning guide disguised as a cookbook that teaches the way to grasp any talent shortly utilizing cooking because the automobile for accelerated studying rules.

Manufacturers, Corporations, and Merchandise

• Nanoblocks: A micro-sized constructing block system from Japan that makes LEGO appear like large boulders.
• LEGO: A line of plastic building toys that naked ft have been stepping on since 1958.
• Coyote: A card sport I made for strategic considering and decision-making.
• Qitone: A model of ketone complement powder for metabolic optimization.
• N.O.-Xplode: A pre-workout complement that guarantees to show your health club session right into a managed explosion.
• Bronkaid / Primatene Mist: Over-the-counter medicines containing ephedrine for respiratory reduction.
• Belsomra: A prescription sleep treatment (a DORA) that helps quiet the mind’s wake sign.
• Mounjaro / Zepbound: Model names for Tirzepatide, a GLP-1 agonist treatment for diabetes and weight administration.
• Thorne: A well being and know-how firm that sells research-backed dietary supplements.
• Taser: A model of carried out power weapon manufactured by Axon Enterprise.
• Ring: A house safety and good dwelling firm owned by Amazon.
• Taran Tactical: A firearms coaching firm specializing in aggressive taking pictures strategies.
• Anduril: A protection know-how firm constructing autonomous methods for army purposes.
• Cloudflare: An internet infrastructure and web site safety firm that retains the web working easily.
• Instruments for Humanity: The corporate behind Worldcoin and the retina-scanning Orb for international identification verification.
• Oura Ring: A wise ring that tracks sleep and bodily exercise with spectacular accuracy.
• Peloton: An train tools and media firm that introduced the boutique health expertise dwelling.
• Fitbit: An organization producing exercise trackers and smartwatches, now owned by Google.
• Domino’s Pizza: An American multinational pizza restaurant chain identified for supply innovation.
• Coca-Cola: A multinational beverage company that has been refreshing the world since 1886.
• Andreessen Horowitz (a16z): A enterprise capital agency that backs daring entrepreneurs constructing the longer term.
• True Ventures: A enterprise capital agency centered on early-stage know-how firms.
• Roblox: An internet sport platform and sport creation system the place customers construct digital worlds.
• Amazon / Amazon Prime / Amazon Pharmacy: E-commerce and know-how firm that began with books and now sells all the things.
• Costco: A multinational company that operates a series of membership-only big-box retail shops.
• Walmart / Goal: Multinational retail companies competing for America’s buying {dollars}.
• UPS: A multinational transport and receiving and provide chain administration firm in distinctive brown vans.
• 1-800-FLOWERS: A floral and gourmand meals present retailer that pioneered phone-based ordering.
• Etsy: An e-commerce web site centered on handmade or classic gadgets and craft provides.
• Bugatti: A luxurious sports activities automotive producer that creates automotive artwork for the ultra-wealthy.

Establishments and Organizations

• Alcoholics Nameless (AA): A world fellowship of people that share their expertise, power and hope with one another that they could clear up their widespread downside and assist others to get well from alcoholism.
• Stanford College: A personal analysis college in Stanford, California, based in 1885 and persistently ranked among the many world’s prime educational establishments.
• Johns Hopkins College: A personal analysis college in Baltimore, Maryland, based in 1876 and broadly thought-about America’s first analysis college.
• TSA (Transportation Safety Administration): A federal company throughout the US Division of Homeland Safety accountable for defending the nation’s transportation methods and making certain freedom of motion for individuals and commerce.

Web sites, Platforms, and Apps

• Leangains: Martin Berkhan’s web site on intermittent fasting.
• YouTube: An internet video sharing and social media platform.
• TikTok: A brief-form video internet hosting service.
• Instagram: A photograph and video sharing social networking service.
• Fb: An internet social media and social networking service.
• Reddit: A social information aggregation, content material score, and dialogue web site.
• Wikipedia: A free, multilingual on-line encyclopedia.
• Digg: A information aggregator with a curated entrance web page.
• Coyote: The official web site for the cardboard sport Coyote.
• River: An in-person occasion and social platform for communities.
• Cursor / Claude Code: AI-powered coding instruments.
• Lovable (previously Base44): “Vibe coding” platforms for constructing apps.
• Vercel: A cloud platform for frontend frameworks and static websites.

Ideas and Phrases

• 12-Step Packages: A set of guiding rules for restoration from habit, most famously utilized by Alcoholics Nameless and different restoration organizations worldwide.
• Ketogenic Weight loss plan (Keto): A high-fat, low-carbohydrate food plan that forces the physique to burn fats for gas as a substitute of glucose, initially developed to deal with epilepsy.
• Intermittent Fasting (16/8): An consuming sample that cycles between durations of consuming and fasting, with the 16/8 technique involving 16 hours of fasting and an 8-hour consuming window.
• Zone 2 Coaching: Low-intensity cardio train carried out at a selected coronary heart fee zone that maximizes fats burning and mitochondrial effectivity.
• APoE (Apolipoprotein E) Gene: A gene related to the chance of creating Alzheimer’s illness, with the APOE4 variant considerably rising susceptibility to cognitive decline.
• Oral Glucose Tolerance Take a look at (OGTT): A medical check to evaluate how the physique processes glucose over time, generally used to diagnose diabetes and prediabetes.
• ApoB (Apolipoprotein B): A main protein part of LDL (“unhealthy”) ldl cholesterol particles, thought-about a extra correct marker for heart problems danger than conventional ldl cholesterol assessments.
• Autophagy: The physique’s mobile “housekeeping” strategy of breaking down and recycling broken proteins and organelles to take care of mobile well being and longevity.
• Exogenous Ketones: Ketone dietary supplements taken orally to quickly induce ketosis with out following a strict ketogenic food plan, although their effectiveness stays debated.
• GLP-1 Agonists: A category of medicines that mimic the hormone GLP-1, used for treating kind 2 diabetes and weight problems by regulating blood sugar and urge for food.
• DORA (Twin Orexin Receptor Antagonist): A more moderen class of sleep medicines that work by blocking orexin receptors within the mind to advertise pure sleep patterns with fewer uncomfortable side effects than conventional sleep aids.
• ECA Stack: A controversial and now largely banned complement mixture of ephedrine, caffeine, and aspirin as soon as common amongst bodybuilders for fats loss however related to severe well being dangers.
• Vibe Coding: A contemporary strategy to programming that depends closely on AI instruments and intuitive problem-solving quite than conventional pc science fundamentals, enabled by superior code era AI.
• Lifeless Web Concept: A conspiracy idea suggesting that the web is now predominantly populated by bots and AI-generated content material quite than genuine human interplay.
• ZK Proofs (Zero-Data Proofs): A cryptographic technique that enables one celebration to show they know particular data with out revealing the knowledge itself, essential for privacy-preserving blockchain purposes.
• DEXA Scan: A low-radiation X-ray scan that exactly measures bone density, physique fats share, and lean muscle mass, thought-about the gold customary for physique composition evaluation.
• Enterprise Capital: A type of personal fairness financing the place traders present capital to startups and early-stage firms with excessive development potential in alternate for fairness possession.

SHOW NOTES

• [00:00:00] Begin.
• [00:06:54] Kevin celebrates 100 days sober! Why and the way?
• [00:15:16] Nanoblocks: Kevin’s new Japanese micro-building pastime.
• [00:18:16] The Sluggish TV motion and Craig Mod’s ambient recordings.
• [00:20:58] Craving analog experiences and wilderness trekking.
• [00:22:24] Writing with background motion pictures.
• [00:23:42] Excessive hopes for The Bare Gun reboot.
• [00:24:35] Kevin’s improved communication since quitting alcohol.
• [00:26:28] My well being interventions for cognitive safety.
• [00:29:00] How ketogenic food plan and 16/8 intermittent fasting led to my finest lab leads to 10+ years.
• [00:33:35] Weight management regimens we don’t advocate.
• [00:39:51] Exogenous ketones: Qitone vs. premium choices.
• [00:50:32] How glucose tolerance assessments work.
• [00:51:58] Microdosing GLP-1 (tirzepatide) for glucose management.
• [00:54:12] DORA sleep medicines and neuroprotective results.
• [00:56:55] Belsomra trial and value concerns.
• [00:57:52] Sauna temperature optimization primarily based on Rhonda Patrick’s analysis.
• [01:00:28] There are not any organic free lunches.
• [01:03:27] The time Kevin discovered a homeless particular person in his closet.
• [01:06:11] Fashionable dwelling safety and privateness measures.
• [01:19:42] Pondering how we survived childhood.
• [01:24:23] AI-driven enterprise capital panorama adjustments.
• [01:28:59] Vibe coding revolution: $250k initiatives now price $50.
• [01:34:28] Training recommendation for youths within the AI age.
• [01:36:27] Empowering inventive minds vs. conventional technical roles.
• [01:38:29] What Kevin’s crystal balls say about Cloudflare’s knowledge market for content material creators.
• [01:42:02] The Digg reboot with Alexis Ohanian: a concentrate on in-person connections.
• [01:42:59] Lifeless web idea and bot content material proliferation.
• [01:43:25] Verifying humanity: the belief gradient.
• [01:54:28] My reduction on the profitable launch of Coyote.
• [01:58:03] Kevin’s Roblox habit and Develop a Backyard bills.
• [01:59:56] Future meetup plans and parting ideas.