On this episode, we focus on:
- What collagen is and why it issues
- Collagen for pure magnificence: pores and skin, hair, and nails
- Joint and bone well being advantages of collagen
- Collagen’s Position in Muscle Restoration and Athletic Efficiency
- Collagen and intestine well being
- Enhancing sleep high quality with collagen
- How to decide on the fitting collagen complement
- Cautions and issues of collagen supplementation
Present notes:
- “Results of Oral Collagen for Pores and skin Anti-Getting older: A Systematic Evaluate and Meta-Evaluation” by Pu, et al.
- “Collagen Supplementation for Joint Well being: The Hyperlink between Composition and Scientific Information” by Martínez-Puig, et al.
- “Impact of collagen supplementation on knee osteoarthritis: An up to date systematic overview and meta-analysis of randomized managed trials” by Simental-Mendía, et al.
- “Efficacy of undenatured collagen in knee osteoarthritis: Evaluate of the literature with restricted meta-analysis” by Kumar, et al.
- “The Results of Sort I Collagen Hydrolysate Supplementation on Bones, Muscle tissue, and Joints: A Systematic Evaluate” by Brueckheimer, et al.
- “A randomized managed trial of the affect of protein supplementation on leg lean mass and muscle protein synthesis throughout inactivity and power restriction in older individuals” by Oikawa, et al.
- “Whey protein however not collagen peptides stimulate acute and longer-term muscle protein synthesis with and with out resistance train in wholesome older ladies: a randomized managed trial” by Oikawa, et al.
- “Collagen peptide supplementation together with resistance coaching improves physique composition and will increase muscle energy in aged sarcopenic males: A randomized managed trial” by Zdzieblik, et al.
- “Collagen peptide supplementation together with resistance coaching improves physique composition and will increase muscle energy in aged sarcopenic males: A randomized managed trial” by Zdzieblik, et al.
- “Particular collagen peptides enhance bone mineral density and bone markers in postmenopausal ladies – A randomized managed examine” by König, et al.
- “Oral supplementation with particular bioactive collagen peptides improves nail development and reduces signs of brittle nails” by Hexsel, et al.
- “It’s worthwhile to eat gelatin: Listed here are the explanation why” by Chris Kresser
- “Collagen dietary supplements might increase nail development and look: Human information”
- “Analgesic efficacy of collagen peptide in knee osteoarthritis: a meta-analysis of randomized managed trials” by Lin, et al.
- “Impression of Particular Bioactive Collagen Peptides on Joint Discomforts within the Decrease Extremity throughout Every day Actions: A Randomized Managed Trial” by Schulze, et al.
- “Oral consumption of particular bioactive collagen peptides reduces pores and skin wrinkles and will increase dermal matrix synthesis” by Proksch, et al.
- “Results of collagen tripeptide complement on pores and skin properties: A potential, randomized, managed examine” by Choi, et al.
- “Introducing licensed grass-fed collagen peptides by SOLUGEL”
- Study extra in regards to the Adapt Naturals Core Plus bundle or take our quiz to see which particular person merchandise finest fit your wants
- Should you’d prefer to ask a query for Chris to reply in a future episode, submit it right here
- Follow Chris on Twitter/X, Instagram, or Fb
Hey everybody, Chris Kresser right here. Welcome to a different episode of Revolution Well being Radio. Right this moment we’re going to dive deep into a subject that’s been in every single place recently– collagen. I think about lots of you listening are already taking a collagen complement. If not, you’re nearly definitely conversant in it from social media and even mainstream sources. However what precisely is collagen and why are so many individuals speaking about it? On this episode, I’ll unpack the science behind collagen and its well being advantages, and allow you to perceive whether or not it’s price incorporating into your individual routine.
Collagen: What It Is and Why It Issues
I need to begin by explaining what collagen is and why it issues. Collagen is essentially the most ample protein within the human physique. It’s fairly actually the stuff that holds us collectively. In truth, the phrase “collagen” comes from the Greek phrase kólla, which means “glue,” as a result of collagen was traditionally used to make glue by boiling animal skins and bones. It acts like a structural glue in our our bodies offering energy and elasticity to our pores and skin, hair, nails, bones, joints, and connective tissues. Should you think about your physique as a home, collagen could be the framework and assist beams. It’s what provides our tissues tensile energy. Some collagen fibers are gram for gram stronger than metal. With out collagen, we’d mainly collapse.
Collagen isn’t a brand new discovery by any means. Our ancestors have been getting loads of it by diets that included pores and skin, cartilage, and bone broth. I typically speak about an ancestral food regimen or nose-to-tail consuming, and collagen is an enormous a part of that. Nonetheless, within the fashionable food regimen, we are inclined to eat loads of lean muscle meats like rooster breasts or steak, and never as a lot of the opposite animal components wealthy in collagen. Because of this, many people aren’t getting a lot collagen from meals anymore. This is perhaps one cause collagen supplementation has taken off. Within the final decade, we’ve seen a speedy rise within the reputation of collagen dietary supplements and powders. Collagen’s gone from one thing solely your grandmother may need talked about, like a cup of bone broth or gelatin dessert, to a virtually $3 billion international “nutricosmetic” trade with powders and gummies and even collagen-infused lattes. It’s a booming pattern, and for good cause. An accumulating physique of analysis means that collagen has a variety of potential well being advantages.
So what are these key advantages? In right now’s episode, we’ll cowl 4 major areas the place collagen makes an enormous distinction. [The first one is] pure magnificence, together with pores and skin, hair, and nails. That is maybe the very best identified use of collagen. We’ll speak about how taking collagen can enhance pores and skin elasticity and hydration, scale back wrinkles, strengthen brittle nails, and even assist hair development. We’ll have a look at some human scientific trials (together with RCTs, or randomized managed trials) that again up these magnificence claims.
The second is joint and bone well being. Collagen’s a significant element of our cartilage and bones. I’ll clarify how supplemental collagen may assist rebuild cartilage, scale back joint ache and stiffness in osteoarthritis and different situations, and even enhance bone density over time. That is about growing old gracefully and preserving our joints resilient.
The third class is muscle restoration and efficiency. This one may shock some individuals as a result of collagen isn’t a typical muscle constructing protein like whey, however we’ll speak about the way it can assist muscle tissue and connective tissue restoration, assist post-exercise restore, and presumably enhance muscle mass or energy when mixed with resistance coaching, particularly in older adults.
The fourth class is intestine and sleep well being. These are two extra surprising advantages of collagen as a result of one in all its key amino acids, glycine, can assist a wholesome intestine lining and enhance digestion and should promote higher sleep high quality. We’ll speak about how glycine works to heal the intestine and the way it acts as a relaxing neurotransmitter that will help you sleep.
By the tip of this episode, it is best to have a transparent image of what collagen can and might’t do. My purpose is to provide you a balanced, nuanced, and naturally, evidence-based take. As at all times, I’ll keep away from any hype or excessive claims. Collagen isn’t a miracle cure-all, though typically it might probably really feel that method, and I’ll share a number of private anecdotes about that. But it surely’s a promising device we are able to use as a part of a holistic, useful medication method to well being. I’ll additionally share some sensible suggestions like how to decide on a top quality collagen complement. For instance, why grass-fed collagen is perhaps higher and what to search for on labels, how one can take it for finest absorption, how a lot to take, and any precautions to pay attention to, which luckily within the case of collagen are only a few. I’ll additionally share some scientific anecdotes from my apply as an instance how collagen could make a distinction in actual life.
So whether or not you’re contemplating collagen for smoother pores and skin, stronger joints, or a more healthy intestine, stick round. Let’s soar into the fascinating world of collagen and see what the science actually says.
Collagen for Pure Magnificence: Pores and skin, Hair, and Nails
Let’s soar proper in with the profit that put collagen on the map for lots of people– its affect on our pores and skin, hair, and nails. Should you’ve seen magnificence merchandise touting “magnificence from inside,” collagen is usually entrance and middle in these merchandise. This isn’t simply advertising and marketing fluff. There’s actual science suggesting that collagen can assist pores and skin elasticity and hydration, scale back wrinkles, strengthen nails, and maybe even thicken hair. About 75 % of the dry weight of our pores and skin is collagen. It’s the protein that offers pores and skin its construction and firmness. As we age, our our bodies produce much less collagen, and the collagen we do have breaks down. This lack of collagen is an enormous cause why we get wrinkles, sagging, and drier pores and skin as we become old.
The concept behind taking collagen dietary supplements is they supply the constructing blocks, and presumably indicators, to assist the physique replenish or restore collagen within the pores and skin. Fairly a number of randomized managed trials, or RCTs, have been achieved on collagen dietary supplements and pores and skin growing old. For instance, research have discovered that taking hydrolyzed collagen, often within the vary of two.5 to 10 grams per day, for 8 to 12 weeks can result in important enhancements in pores and skin elasticity and hydration, and even a discount in wrinkle depth. In a single systematic overview of 26 research with over 1,700 members, researchers concluded that collagen supplementation persistently improved pores and skin hydration and elasticity, with the results turning into important after about eight weeks of each day use. In plainer phrases, after two months of normal collagen use, individuals’s pores and skin tended to be extra hydrated.
Some research additionally present wrinkle discount. As an example, a trial may measure the depth of crow’s toes wrinkles earlier than and after collagen supplementation and discover that the collagen group’s wrinkles are notably shallower than the placebo teams after two to 3 months. That’s fairly outstanding, contemplating we’re speaking about an oral complement and never a topical cream or a process. And in reality, the theme of this podcast and the theme of the analysis is that inner dietary supplements –oral dietary supplements– truly are more practical than topical lotions. If you concentrate on it, this is smart as a result of true well being comes from inside. If now we have a disrupted intestine microbiome, for instance, that’s contributing to irritation, that may present up in our pores and skin as a result of our pores and skin is the biggest organ system within the physique. So it doesn’t matter what you place in your pores and skin, if in case you have that underlying root trigger that’s driving irritation within the pores and skin, the topical stuff could have restricted outcomes. Whereas in the event you take one thing internally to deal with that root explanation for irritation, then it can result in higher, more healthy pores and skin, hair, and nails with out even needing to place one thing on topically.
So let’s discuss in regards to the mechanisms for collagen and wonder from inside. The collagen we ingest doesn’t simply magically paste itself into our pores and skin. While you ingest collagen peptides, [which are] mainly collagen damaged down into smaller items, these peptides and amino acids get absorbed into the bloodstream. Analysis means that a few of these collagen fragments, particularly dipeptides like proline-hydroxyproline, can journey to pores and skin tissue and sign pores and skin cells like fibroblasts to ramp up collagen manufacturing or restore. Consider these collagen peptides as messengers that inform your pores and skin, “Hey, produce extra collagen and maintain on to moisture.” On the identical time, the amino acids like glycine and proline function uncooked supplies for constructing new collagen fibers. Collagen dietary supplements have additionally been proven to extend the density of collagen fibers within the pores and skin and the exercise of fibroblasts, [which are] the cells that make collagen. This twin motion, offering the constructing blocks on one hand and sending indicators alternatively, is probably going why we see enhancements in pores and skin metrics like elasticity (pores and skin bouncing again extra readily) and hydration (pores and skin holding extra moisture so it appears to be like plumper).
One other attention-grabbing factor right here [is that] some analysis means that collagen dietary supplements may assist shield the pores and skin from inside. There’s proof from animal research and a few human information that collagen peptides may improve the pores and skin’s pure barrier perform, stopping leaky pores and skin, and even affords some safety in opposition to UV-induced pores and skin growing old.
Collagen’s advantages aren’t simply pores and skin deep. Many individuals report stronger nails and higher hair when taking collagen, and there’s undoubtedly information to again this up, particularly for nails. Should you battle with brittle nails that chip or peel simply, collagen may assist. A small 2017 examine on 25 ladies discovered that about six months of each day collagen supplementation led to important enhancements in nail development and lowered brittleness. In truth, nearly 90 % of the members reported that their nails have been longer and fewer brittle after the therapy. A lot of them noticed their nails rising quicker and breaking much less. The researchers additionally famous that the advantages continued for as much as a month after they stopped taking the collagen, suggesting some lasting enchancment in nail high quality. Now this wasn’t a placebo-controlled trial, it was an open-label examine, but it surely’s promising and it is smart biologically– nails, like pores and skin, include collagen within the nail mattress, and offering these further amino acids may strengthen nail construction.
For hair, the proof is extra anecdotal at this level, however there are believable causes collagen may assist. Hair is fabricated from keratin (one other protein), not collagen. However collagen might profit the hair not directly by supporting the pores and skin and connective tissue that the hair grows from, for the reason that hair follicles are within the dermal layer of the pores and skin, which is wealthy in collagen. Some preliminary research and plenty of testimonials recommend collagen may result in thicker or faster-growing hair, however we’d like extra managed analysis right here. Nonetheless, on condition that collagen peptides present amino acids like proline, which is used to supply keratin, it’s definitely potential that taking collagen provides a few of the vitamins wanted for hair development. In any case, pores and skin and nail advantages are essentially the most well-substantiated advantages to this point.
Earlier than shifting on, let me share a fast private anecdote. I’ve had sufferers in my apply, significantly middle-aged ladies, who began taking collagen primarily for joint ache or intestine well being. However then a number of months later they’re saying one thing like, “Chris, my pores and skin appears to be like higher and my hairstylist observed my hair is thicker.” This has occurred so many occasions, I’ve misplaced rely. It’s nice when a useful medication intervention can handle a number of points directly. In my very own life, I’ve observed that once I’m frequently incorporating collagen, my pores and skin doesn’t get as dried out within the winter. I stay in a extremely dry, excessive desert winter local weather and so my pores and skin can get fairly dry within the winter months. And once I take collagen frequently, which I do, I discover this doesn’t occur as a lot.
Joint and Bone Well being Advantages of Collagen
Let’s transfer on from magnificence to joint and bone well being, one other large cause individuals flip to collagen. Should you endure from achy joints, osteoarthritis, otherwise you’re involved about osteoporosis or bone loss, collagen is certainly price a glance. That is an space I’m personally fairly enthusiastic about as a result of I had a big damage final summer season, as a few of you recognize in the event you’ve been listening to my podcast for awhile or getting my emails, and I believe that common collagen along with omegas, curcumin, and different vitamins was an enormous a part of my potential to get better rapidly. It was fairly surprising to the orthopedist that I noticed. I used to be in a position to bounce again inside a matter of weeks and absolutely get better previous to the ski season beginning in November. My damage was in late August. I used to be in a position to keep away from surgical procedure and was absolutely recovered by the point ski season began, and I’ve skied most likely 60 days this season already and have had no issues with my again. I actually imagine that collagen and a few of the different vitamins that I took throughout that interval have been instrumental in my restoration course of. And that has a big impact on my high quality of life and my happiness and each day well-being, to have the ability to get better that rapidly from an damage and keep energetic.
Osteoarthritis, the wear-and-tear form of arthritis, entails a breakdown of cartilage and joints, resulting in ache and stiffness. Cartilage is the graceful, rubbery tissue that covers the tip of bones in our joints, permitting them to glide over one another. And guess what? Cartilage is made largely of collagen, particularly Sort II collagen in articular cartilage. As cartilage degrades in osteoarthritis, a few of these collagen fibers are misplaced or broken. The concept of utilizing collagen dietary supplements for joint well being is that offering these collagen peptides may give the cartilage forming cells, that are known as chondrocytes, the constructing blocks to restore or keep cartilage, and may also have an anti-inflammatory impact within the joint. Medical research have examined collagen, typically within the type of collagen hydrolysate, for joint ache and numerous them have proven constructive outcomes, particularly for knee osteoarthritis. A current meta-analysis of research in 2023 checked out a number of RCTs and concluded that collagen peptide supplementation led to important ache reduction in sufferers with knee osteoarthritis in comparison with a placebo. And what’s encouraging is that this got here with out important negative effects. The evaluation discovered no distinction in adversarial occasions between collagen and the placebo teams, indicating that collagen was as protected as a dummy capsule in these trials. That’s big as a result of so most of the medicines like ibuprofen and different NSAIDs [used by] individuals who have arthritis have important negative effects and long-term dangers.
Again to those trials, meta-analysis, a few of the trials within the evaluation used round 10 grams of collagen hydrolysate per day for a interval of three to 6 months and noticed fairly important enhancements in joint ache and performance. Past ache, there’s proof that collagen can enhance joint perform and mobility. Some trials have members do issues just like the Stanford strolling take a look at or measure how far they will stroll in six minutes. And collagen teams typically carry out higher after the supplementation interval.
There are additionally research on youthful athletic populations. As an example, one examine on energetic athletes discovered {that a} particular collagen peptide complement lowered joint discomfort with train and improved restoration. So this implies collagen shouldn’t be just for older adults with arthritis, it’d assist anybody whose joints are below loads of stress. That’s the place I characterize myself for now. I don’t have arthritis or any form of bone degeneration, however I’m extraordinarily energetic, snowboarding, mountain biking, energy coaching, paddle boarding, climbing, backcountry actions, all types of stuff that places loads of stress on my physique. So I’ll take any benefit I can get that enables me to take care of that top exercise degree as a result of it’s such an enormous a part of my psychological well being and my enjoyment of life.
After we digest collagen, some peptides may accumulate in joint cartilage or stimulate cells within the joint. Collagen’s amino acids like proline and glycine are additionally utilized by the cells to construct an extracellular matrix, which is a scaffold of cartilage, and collagen might have a light anti-inflammatory impact. Glycine, for instance, has been proven to cut back irritation and oxidative stress. Within the gelatin article I wrote some time again, I discussed that gelatin, which has loads of collagen in it, appears to have an impact that inhibits the breakdown of cartilage and even boosts cartilage metabolism. Collagen additionally comprises lysine, an amino acid that helps your physique take up calcium and kind collagen. Apparently, lysine has been proven in animal research to hurry up fracture therapeutic. So collagen is bringing loads of useful constituents to the desk for joint integrity and bone well being.
On a sensible observe, I’ve seen sufferers with delicate osteoarthritis who begin taking collagen and are available again a number of months later with much less knee ache or much less joint ache general and higher mobility. One affected person of mine in his fifties was an avid tennis participant. He mentioned that after three months of each day collagen peptides, he may play longer matches with much less knee stiffness the following day. As lots of you recognize, I strained my pes anserine and medial collateral ligament final summer season taking part in pickleball. I obtained the pickleball bug like so many others and went from not taking part in any courtroom sports activities for 20 years to taking part in two hours a day, 5 – 6 days every week. I took 10 grams of collagen twice a day as a part of my restoration, and I believe it made an enormous distinction. I had a little bit of a tough summer season with that knee damage and again damage. Maybe I used to be overdoing it a bit of bit, however collagen made an enormous distinction in my restoration as a result of as we’ve mentioned, it helps rebuild connective tissues like tendons and ligaments, which turns into more and more tougher for the physique to do by itself as we age.
In truth, it’s not a nasty concept to take collagen about an hour earlier than rehab workouts or bodily remedy to focus on these vitamins to the tissues that you simply’re engaged on. That’s a bit of bio hack that may improve collagen deposition in injured tendons or ligaments, primarily based on preliminary analysis and the collective expertise of loads of actually expert bodily therapists.
Let’s speak about bones now. It would shock you, however bones are about one-third collagen by quantity. Collagen types the natural matrix of bone – think about the rebar framework in a constructing – after which minerals like calcium and phosphorus stick with that matrix to make the bone sturdy and onerous. As we age, or particularly in postmenopausal ladies, bone density can decline. That is known as osteopenia initially, after which it might probably progress to osteoporosis. Whereas calcium, vitamin D, vitamin K2, and different minerals get loads of consideration for bone well being, collagen is a important and sometimes neglected element. In case your collagen matrix is weak, including extra calcium is like packing concrete onto a crumbling mesh. It’s worthwhile to strengthen the mesh itself.
There’s compelling analysis indicating that collagen supplementation can enhance bone mineral density. One notable examine, an RCT revealed in Vitamins in 2018, concerned post-menopausal ladies with age-related bone loss. They gave one group 5 grams of particular collagen peptides each day and the opposite group a placebo for 12 months. After a 12 months, the collagen group had important will increase in bone mineral density of their backbone and femoral neck, which is the hip, in comparison with the placebo group, which truly misplaced bone density as anticipated. To place this in perspective, the collagen group’s bone density went up whereas the management group’s went down. The ladies taking collagen additionally had favorable adjustments of their bone biomarkers. Blood checks confirmed a rise in a bone formation marker and a lower in a bone degradation marker. This implies that collagen was tipping the dimensions towards constructing new bone moderately than dropping it, which is precisely what the examine outcomes discovered. For a dietary complement to have that impact is fairly spectacular. Sometimes you’d anticipate perhaps a slowing of bone loss, however right here we noticed precise beneficial properties in bone mineral density.
One other examine prolonged this sort of analysis over an extended interval. In a follow-up, if I recall accurately, some researchers checked out collagen over 4 years and located continued profit, implying that long-term use may maintain including up. And once more, collagen is protected and well-tolerated, making it a pleasant adjunct to different bone well being methods. For somebody involved about osteoporosis, I take into account collagen as a bit of the puzzle, together with resistance coaching, enough calcium, vitamin D, K2, magnesium, and different vitamins. It’s not a substitute for these, but it surely addresses that collagen matrix side straight.
Basically, collagen gives a assist system for our musculoskeletal well being. It retains the cartilage and joints sturdy and fewer infected, and it helps bones keep dense and resilient. Collagen won’t change meds and different therapies if in case you have extreme arthritis ache, however over the span of months, it may scale back your want for these meds by bettering the underlying subject. And for bone, collagen isn’t going to be as potent as, say, prescription osteoporosis medicines in somebody with very low bone mineral density, however medicines can have important negative effects and solely handle one side of bone well being. Collagen, being dietary, works extra slowly however helps your physique’s pure bone constructing processes and has just about no draw back. A balanced holistic method is perhaps utilizing collagen to nourish the joints and bones, train to stimulate them, as a result of bones and cartilage reply to the stress of train by getting stronger, after which together with different vitamins and life-style components to assist tissue well being like an anti-inflammatory, nutrient-dense food regimen, sustaining a wholesome weight to cut back joint load, and so forth. And collagen suits very well into that form of holistic method.
Earlier than shifting on, I need to rapidly point out [that] in the event you’re already consuming a food regimen wealthy in connective tissue or bone broth, you might be undoubtedly getting a few of these advantages of collagen and not using a complement. For instance, a long-simmered bone broth is actually a collagen complement in whole-food kind as a result of it’s wealthy in gelatin. I typically encourage meals as medication first, as you recognize. However realistically, not everybody has the time or style for bone broth each day and digesting gelatin could be tough for some individuals, particularly these with poor digestion or digestive situations that restrict absorption. So that they might not be getting as a lot collagen from the gelatin as they want, and supplementation can nonetheless actually make sense in that context.
Collagen’s Position in Muscle Restoration and Athletic Efficiency
All proper, let’s transfer on to the third class of collagen profit which is muscle restoration and efficiency. This one’s actually attention-grabbing as a result of if you recognize diet, you recognize that collagen shouldn’t be an entire protein. It’s truly low in important amino acids like leucine and doesn’t include any tryptophan in any respect. So that you wouldn’t consider collagen as a muscle-building protein. And certainly, in the event you’re a bodybuilder or athlete that does loads of energy coaching, collagen alone shouldn’t be your major protein supply for muscle beneficial properties. You’d need whey and muscle meat, and so forth, to have the complete spectrum of amino acids. Nonetheless, collagen can nonetheless play a supportive function in muscle well being and restoration, primarily by serving to restore connective tissues like tendons, ligaments, and fascia, and presumably by sustaining lean muscle mass in older adults or throughout damage restoration. One key amino acid in collagen, glycine, is definitely essential for muscle and metabolic well being.
Glycine makes up roughly a 3rd of collagen’s amino acid content material. Analysis has proven glycine helps with the synthesis of creatine, for example, and might forestall muscle losing in sure situations. In truth, one cause muscle meats alone can typically be problematic in extra is their excessive in methionine relative to glycine. With out sufficient glycine, you may get extra homocysteine and presumably extra irritation. Collagen helps stability that out by offering glycine. There’s proof that glycine within the food regimen reduces age-related muscle loss, which known as sarcopenia. So consider collagen as an oblique helper. It’s not going to spike muscle protein synthesis like a whey shake, but it surely creates a metabolic surroundings that’s pleasant to muscle upkeep and development.
Now on to research. A notable RCT revealed in 2015 checked out collagen peptide supplementation mixed with resistance coaching in aged males with sarcopenia. That they had a bunch of older males do 12 weeks of energy coaching. Half of them obtained 15 grams of collagen protein after exercises, the opposite half obtained a placebo. By the tip, the entire males gained muscle and misplaced fats from the train. No shock there. However the collagen supplemented group did considerably higher. They gained extra fat-free muscle mass and energy than the placebo group. Particularly, the collagen group gained about 4.2 kilograms of lean mass versus 2.9 kilograms within the placebo group. In addition they had a better improve in leg energy. That’s a fairly large distinction attributable to only including collagen peptides. The authors concluded that collagen can improve the results of train on physique composition, serving to improve muscle mass and reduce fats past train alone.
Why may that be? Properly, there’s a number of hypotheses. One, these older people may need been protein poor to begin, so any further protein helps. Collagen on this case served as a supplemental protein supply to gasoline muscle constructing. Two, collagen’s glycine and arginine content material may assist creatine manufacturing and development hormone launch, aiding muscle restoration. Three, collagen may very well be strengthening the connective tissue in and round muscle, like tendons that connect muscle to bone. Stronger connective tissue may permit for higher drive switch throughout exercises and scale back damage, not directly serving to muscle development and efficiency. Additionally, in case your joints and tendons really feel good, you’ll be able to push tougher in coaching. So collagen is perhaps fortifying the assist system that your muscle tissues depend on once you elevate weights or run or do any exercise.
There’s additionally analysis for athletes. For instance, a small examine checked out athletes with continual ankle instability and located collagen supplementation improved ankle stability and lowered ache. One other space is damage restoration. There’s an rising protocol the place athletes with tendinopathies like Achilles tendon points are given collagen plus vitamin C earlier than doing their rehab workouts to stimulate therapeutic within the tendon. The science behind this comes from each human and animal research exhibiting collagen consumption can improve collagen synthesis in ligaments or tendons when paired with loading train. It’s a bit past the scope of this podcast to dive absolutely into, however the take-home is that collagen is more and more utilized in sports activities diet for damage prevention and restoration. From a efficiency standpoint, whereas collagen gained’t straight increase your VO2 max or one thing like that, it might probably contribute to quicker restoration post-exercise. Many individuals report much less soreness or joint ache after onerous coaching after they embody collagen, myself included, which suggests you may get again to coaching sooner or with extra consistency. Additionally, if collagen helps you sleep higher, which we’ll focus on shortly, that not directly improves restoration, since sleep is when your physique heals and builds muscle.
To summarize, collagen can assist muscle restoration and assist efficiency not directly by strengthening connective tissues and offering key amino acids for restore. It’s been proven to amplify muscle development and energy beneficial properties in older adults when mixed with train, probably by guaranteeing sufficient protein constructing blocks and by defending in opposition to muscle breakdown. For youthful of us or athletes, collagen may assist maintain joints and tendons wholesome, [meaning] much less damage [and] extra constant coaching, and presumably enhance restoration so you’ll be able to practice onerous once more sooner. Simply bear in mind, collagen shouldn’t be a standalone muscle gasoline. Consider it as a specialised complement that enhances your major protein consumption and coaching routine.
Collagen and Intestine Well being: Therapeutic from Inside
The final set of advantages we’ll focus on are intestine well being and sleep high quality. These might sound unrelated, however they share a typical hyperlink by an amino acid I’ve talked about a number of occasions on this podcast, glycine. Collagen is roughly glycine by composition, and glycine is a fairly outstanding amino acid. It has roles in digestive well being and within the nervous system that impacts sleep.
A lot of you who comply with my work know I typically emphasize intestine well being as the muse of general well being. Leaky intestine, GERD, IBS, ulcers – these are frequent points. It seems that collagen and gelatin could be very soothing for the intestine. Keep in mind that collagen’s wealthy in glycine, proline, and glutamine, [which are] all amino acids that assist the intestine lining. Glycine and glutamine particularly are utilized by the cells of the gastrointestinal tract as gasoline and as constructing blocks to regenerate the intestinal lining. Glycine additionally stimulates gastric acid secretion, which is attention-grabbing as a result of having adequate abdomen acid is essential for correct digestion. Low abdomen acid can result in heartburn, imagine it or not, in addition to poor protein digestion and dysbiosis.
Analysis means that collagen peptides may also help restore the integrity of the intestine lining. A method they do that is by enhancing the manufacturing of mucus within the abdomen and bettering the mucosal barrier that protects the intestine wall. There was a examine in rats exhibiting gelatin may shield in opposition to ulcers by basically coating and therapeutic the abdomen lining. In people, there’s proof, a few of it oblique or scientific observations, however proof nonetheless, {that a} food regimen wealthy in gelatin and collagen helps with situations like leaky intestine syndrome. In my very own scientific apply, I’d typically see enhancements in sufferers with IBS or intestinal permeability once we added bone broth or collagen dietary supplements. And certainly, in the event you’re conversant in the GAPS food regimen, it’s closely primarily based on bone broth and it’s designed for individuals with important digestive points like Crohn’s illness or ulcerative colitis. These sufferers report much less bloating, higher stool consistency, and an general calmer digestive system.
As a particular instance, I had a affected person with long-standing ulcerative colitis, which is an autoimmune inflammatory bowel situation. As a part of her diet plan, we included each day collagen peptides, about 10 grams twice a day in her case, together with a nutrient-dense, anti-inflammatory food regimen with loads of bone broth. Over a number of months, her flare-ups lowered and her colonoscopy confirmed improved mucosal therapeutic. Now once more, we are able to’t credit score collagen alone, as a result of we did loads of issues, however given what we learn about glycine’s function in modulating irritation and serving to tissue restore, I strongly suspect it was a significant contributor to the therapeutic surroundings in her intestine.
It’s additionally price noting that gelatin absorbs water and helps maintain fluid within the digestive tract. This may enhance intestinal transit and regularity. It’s just like how soluble fiber works. Gelatin can bind to water and assist that good, wholesome motion by the bowels. So if somebody suffers from constipation, a little bit of gelatin or collagen plus enough hydration may assist. In a nutshell, collagen is gut-friendly. It could improve gastric juices, bettering digestion, assist put together the abdomen and intestinal lining, and assist wholesome bowel perform. If in case you have a leaky intestine or are recovering from one thing like gastritis, incorporating collagen by a complement or home made bone broth is without doubt one of the first issues I like to recommend. It’s light and nourishing, form of like an inner bandage in your intestine.
Enhancing Sleep High quality with Collagen
Now onto sleep, one thing we may all most likely use a bit of extra of. How does collagen come into play? Once more, it’s largely by glycine. Glycine is not only an amino acid for constructing proteins, it additionally acts as an inhibitory neurotransmitter within the mind. Which means it might probably assist calm the nervous system. In truth, glycine can cross the blood-brain barrier and has been proven to extend serotonin ranges in sure mind areas and assist regulate physique temperature at evening, each of that are associated to sleep initiation.
There have been some fairly cool research the place they gave individuals with sleep issues a number of grams of glycine earlier than bedtime. The outcomes confirmed measurable enhancements in sleep high quality. Individuals fell asleep quicker, had higher sleep effectivity, and reported much less daytime sleepiness after taking glycine at evening. Sometimes, the efficient dose is round three grams of glycine. Coincidentally, or perhaps not so coincidentally, about two tablespoons of collagen or gelatin gives you roughly three grams of glycine. So taking a serving of collagen within the night may mimic what these research discovered. Glycine seems to assist decrease core physique temperature a bit, which is a sign that facilitates sleep. Our our bodies naturally quiet down a pair levels at evening as we enter deep sleep. It could additionally scale back nervousness and promote a way of calm. And a few individuals even report that taking collagen or gelatin earlier than mattress provides them extra vivid desires or deeper sleep, probably due to glycine’s results on sleep structure.
To be clear, collagen, it’s not a sedative. It’s not like taking melatonin or a sleeping capsule. Its impact is extra delicate. It’s supportive. Should you’re actually wired or have main insomnia, you’ll want to deal with the foundation causes, whether or not that’s stress, blue gentle publicity late at evening, and so forth. However as a part of a wind-down routine, collagen could be a good addition. For instance, you possibly can have a cup of heat natural tea and stir in a scoop of collagen. Not solely are you getting the glycine, you’re additionally giving your physique some protein which might stabilize blood sugar by the evening, which is one other think about sleeping soundly as blood sugar dips can wake you up. I typically will take my collagen at evening in a bit of little bit of water or natural tea about an hour earlier than mattress. And I do discover on nights that I do that, I are inclined to get up much less and really feel a bit extra refreshed. It’s anecdotal for positive, but it surely matches the examine exhibiting three grams of glycine can enhance sleep continuity. A few of my sufferers with delicate insomnia have additionally discovered this to be useful, particularly those that don’t need to take stronger sleep aids or who expertise negative effects after they do.
Yet one more attention-grabbing angle is stress and the HPA axis. Glycine may also help blunt cortisol output in response to emphasize. By calming the nervous system, it might probably not directly assist adrenal well being and a extra balanced stress response, which in flip helps sleep. It’s all linked – intestine, mind, sleep, stress – and collagen, and glycine particularly, is a kind of little leverage factors that may positively affect a number of programs. So for intestine and sleep, collagen helps a wholesome intestine lining and digestion, which might enhance nutrient absorption and scale back GI points. And collagen’s excessive glycine content material helps promote leisure and higher sleep high quality. If in case you have hassle along with your intestine or hassle sleeping, collagen can provide some reduction for each – heal your intestine and assist your sleep by the evening. It’s not typically we discover one thing that advantages so many various areas, however the human physique is advanced and these programs interrelate.
Selecting the Proper Collagen Complement: High quality, Sourcing, and Dosage
By now you’re hopefully satisfied that collagen’s a minimum of price a attempt in the event you haven’t tried it already and also you’re not already taking it, given its wide-ranging advantages. However as with every complement, not all collagen dietary supplements are created equal. High quality issues loads. On this part, I need to information you thru what to search for in a collagen complement, the significance of peptide dimension, or molecular weight, for absorption, how one can dose it and the way lengthy to take it to see outcomes, and why sourcing, particularly selecting grass-fed collagen, could make a distinction each in your well being and for the planet. I’ll additionally spotlight an ingredient known as SOLUGEL® licensed grass-fed collagen, which is exclusive within the trade.
Let’s begin with bioavailability and discuss a bit of bit about why peptide dimension issues relating to collagen. While you’re buying round for collagen, you’ll typically see the time period “hydrolyzed collagen” or “collagen hydrolysate” or “collagen peptides.” This implies the collagen, which is often extracted from animal hides, bone, or fish scales, relying on the supply, has been damaged down with enzymes or different strategies into smaller peptides.This course of makes the collagen way more digestible and absorbable. Complete collagen or gelatin, like consuming a bit of gristle, is a big protein construction and your physique would have a tough time absorbing it intact. However collagen peptides, usually with a molecular weight round two to 3 kilodaltons, which may be very small, are simply absorbed within the small gut. In truth, research present these tiny peptides could be detected within the bloodstream inside an hour after ingestion.
Why is 2 kilodaltons typically cited? It’s as a result of peptides of that dimension, roughly containing just some amino acids, perhaps two to 10 in size, can slip by the intestine lining extra readily than bigger peptides. In addition they appear to have particular organic exercise. For instance, a dipeptide like hydroxyproline–glycine, which is frequent in hydrolyzed collagen, has been discovered to set off cells within the pores and skin, bones, and joints to ramp up collagen synthesis. You bear in mind we talked about collagen as a sign earlier within the present, and this smaller collagen peptide is what gives that signaling. If the collagen was not damaged down, say you simply ate an enormous intact collagen molecule, your digestive system would chop it up randomly and also you won’t get these helpful little signaling peptides.
In essence, smaller peptides means higher bioavailability and efficacy. One paper famous that when individuals take hydrolyzed collagen, about 10 % of it’s absorbed as these small intact peptides that journey within the bloodstream and act as messengers, whereas the remaining is absorbed as free amino acids that present constructing blocks. Each are helpful. The intact collagen fragments are like a blueprint or a nudge to the physique, like, “Hey, repair your collagen right here.” and the free aminos are the uncooked supplies, “Listed here are the bricks to construct with.” This two-fold mechanism is one thing we already touched on with pores and skin well being, but it surely applies to collagen advantages usually.
When evaluating a collagen product, search for mentions of issues like “hydrolyzed,” “peptides,” and even specifics like “common molecular weight of two kilodaltons or 2,000 daltons.” Most respected collagen dietary supplements have achieved the hydrolysis. Should you see one thing like “gelatin,” like the type you’d use to make Jell-O, that’s not absolutely hydrolyzed. It is going to nonetheless work, but it surely gained’t dissolve in chilly liquids and it’s not as simply absorbed except you totally warmth it. Gelatin is nice for making gummies or in cooking, however for each day supplementation, collagen peptides are extra user-friendly. Additionally examine if the model gives any data on how they guarantee high quality. Do they take a look at for heavy metals? Is it a trusted supply? Collagen typically comes from bovine sources, typically porcine, or marine sources like fish, or poultry sources. Every has its personal amino acid profile, and allergen issues in fact. For instance, if in case you have a fish allergy, you’d need to keep away from marine collagen.
The whole lot you’ve questioned about collagen in a single episode. The way it impacts pores and skin, joints, intestine well being, muscle restoration, sleep, and the way to decide on the very best complement. It’s all right here on this episode of Revolution Well being Radio. #Collagen #Well being #ChrisKresser #RHR
Bovine is the commonest and tends to have sorts I and III collagen, which is nice for pores and skin, bones, and tendons. Marine collagen is often sort I, additionally good for pores and skin, and typically touted for having smaller peptides, although that basically is determined by the way it’s processed and the very best, highest high quality bovine collagen peptide dietary supplements could have small molecular weight.
So right here’s the underside line. Most hydrolyzed collagen merchandise from respected manufacturers ought to be comparatively well-absorbed, however some collagen components have decrease molecular weight peptides like two kilodaltons or 2,000 daltons. This improves absorption and makes collagen peptides simpler to digest, which could be essential for folk with SIBO, IBS, and different intestine points. I’ve had fairly a number of sufferers in my apply that really feel bloated after taking typical collagen dietary supplements, however after they attempt a product with decrease molecular weight peptides, they don’t expertise that in any respect. One other good thing about low molecular weight is improved solubility. This can be a fancy method of claiming it mixes effectively with water and different drinks. Nobody desires to place collagen of their tea or espresso and have a bunch of clumps floating round. That’s gross. In case your collagen doesn’t combine fully clear, it might imply the molecular weight of the peptides isn’t in that two kilodalton vary.
So let’s discuss sensible suggestions – how a lot collagen to take, how typically, and the way lengthy to keep it up to note advantages. Primarily based on the analysis and my expertise, a typical dosage is round 5 to 10 grams of collagen peptides per day. Many research on pores and skin and joints have used 10 grams each day. Should you’re concentrating on one thing particular like osteoarthritis or osteoporosis, otherwise you’re coping with an acute damage you’re making an attempt to get better from, you may profit from 20 grams a day, break up into morning and night doses. For instance, once I had my knee and again damage, I took 20 grams a day. I’d take 10 grams within the morning after which 10 grams within the night earlier than mattress, and that had the additional benefit of serving to with my sleep. For normal well being or magnificence, 5 grams is perhaps adequate. However in fact, it simply actually is determined by your targets and what you’re aiming for.
As a upkeep dose, personally, I take 10 grams a day. You may break up this, perhaps 5 grams in your morning espresso – lots of people like so as to add gelatin to their espresso or tea – after which 5 grams within the night, once more, to advertise wholesome sleep. Collagen shouldn’t be a stimulant or something. As I mentioned a number of occasions, it might probably enhance sleep, so timing isn’t important. Listed here are one other few suggestions to consider. You may take collagen round a exercise, both earlier than and after, so it might probably provide amino acids for restoration. And as we talked about earlier than, in the event you’re rehabbing an damage, you’ll be able to take it simply earlier than your [physical therapy]. That’s been proven to be helpful. You may take it at evening an hour earlier than mattress to assist sleep. You may take it with meals to assist digestion. You may do the entire above. You may actually unfold it out all through the day as a lot as you need. There’s not likely a big higher restrict. I don’t know that individuals would profit from way more than 20 to 30 grams a day, even when you’ve got intensive acute damage, however there’s a fairly broad latitude to the quantity you could take.
An essential factor to contemplate and bear in mind with collagen is that consistency is essential. It’s not like caffeine the place you’re feeling a direct jolt or impact. It really works regularly to restore and rebuild tissues and scaffolding. In most research, advantages turn out to be noticeable round eight weeks or later. So you actually need to keep it up. For instance, pores and skin elasticity enhancements have been important after eight weeks and much more so after 12 weeks. For bones, we noticed in that examine that it took a 12 months to essentially measure the largest adjustments. And for joints, some RCTs confirmed joint ache discount in three months whereas others wanted as much as six months. It’s to not say that you simply gained’t expertise some advantages earlier. Most individuals do. However you’ll be able to’t actually consider the complete advantages that you simply’re going to get till a minimum of eight weeks, and that’s for pores and skin. For joints, it’s extra like three months to 6 months. And for bones, it may be as much as a 12 months.
And that is smart, proper? The bones are the slowest rising tissues within the physique. So that they want extra time to vary. Whereas pores and skin remodels itself way more rapidly, so you’ll be able to see the complete adjustments earlier relating to pores and skin well being. I often inform individuals [to] give collagen a minimum of three months of each day use to evaluate its results. In fact, you’re going to wish a bit of bit longer than that in the event you’re engaged on bone well being. You will notice some constructive adjustments earlier, perhaps your nails develop quicker after simply 4 weeks, or your intestine feels higher after only a week. However [for] the complete spectrum of advantages, three months is a good trial interval. One of many good issues about collagen is it’s basically a protein meals. So that you don’t usually cycle it on and off such as you may with sure herbs or excessive dose nutritional vitamins. You may take it indefinitely as a part of your each day diet, and many individuals do.
Fast observe on types. Collagen powder is by far the commonest and often essentially the most economical. There are additionally collagen capsules, however to get 5 to 10 grams a day, you’d need to swallow loads of capsules since every capsule most likely solely has 500 milligrams. There’s additionally a rising variety of collagen gummy merchandise, however they often have a bunch of synthetic junk and flavors in them. I’m not an enormous fan of collagen gummies. And once more, it’s important to eat loads of them to get the complete dose. So I actually want powders. They will come unflavored and you’ll combine them in something– water, espresso, smoothie, soup. There are additionally flavored collagens now. However once more, it’s important to be careful for added sugar or synthetic sweeteners or components. To be sincere, pure, unflavored, clear label collagen as the one ingredient is my go-to and what I like to recommend for most individuals. collagen product ought to be tasteless and odorless. As we talked about earlier than, it ought to combine fully clear in water if it has a low molecular weight (or another beverage). If a collagen powder tastes or smells form of funky or has an “animal” aftertaste or scent, that undoubtedly is perhaps a top quality subject or it’s not as hydrolyzed accurately. Collagen peptides, once more, ought to dissolve simply. If it’s clumping or not dissolving, attempt a special model. Slightly trick is to sprinkle the powder on the floor of your liquid and let it sit for 30 seconds earlier than stirring. That may assist it dissolve with out clumping.
Let’s focus on sourcing. This can be a subject I’m captivated with as a result of it intersects well being, ethics, and environmental affect. Collagen dietary supplements are derived from animal components, usually the hides, bones, or scales that may in any other case be byproducts of the meat and fishing industries. Utilizing these components for collagen is a good way to cut back waste and make the most of the entire animal as a result of these components would in any other case be thrown away. Nonetheless, the standard of collagen will solely be pretty much as good as the standard of the animal supply. If the animals have been unhealthy, uncovered to loads of pesticides or antibiotics, or raised inhumanely, that would probably carry over into the product (or a minimum of doesn’t align with the values of many people within the ancestral well being neighborhood). Grass-fed collagen comes from cattle which can be raised on pasture, consuming grass as their main food regimen moderately than in feedlots consuming grain.
Why does this matter? For one, cows are ruminants and their pure food regimen is grass. Once they eat grass, they are typically more healthy and leaner and their tissues may need a special composition. For instance, we all know that the omega-3 to omega-6 ratio is superior in grass-fed beef, and grass-fed beef additionally has greater quantities of different vitamins. With collagen, we’re largely coping with protein, so fatty acid content material isn’t as related, however general animal well being may nonetheless affect the standard of the collagen. Simply as importantly, grass-fed often implies a greater normal of animal welfare – the cows are free vary, they’re not confined in crowded feedlots, and so they’re not pumped with development hormones or pointless antibiotics. From a human well being perspective, selecting grass-fed ensures you’re not ingesting residues of issues like antibiotics or development promotants that is perhaps current in feedlot cattle collagen. It could additionally scale back the chance of issues like [bovine spongiform encephalopathy] (BSE), or mad cow illness. Though that danger is fairly low in fashionable dietary supplements, as they supply components rigorously and sometimes from international locations with no BSE. Grass-fed cattle additionally come from locations the place ranching practices could be regenerative. For instance, loads of grass-fed collagen in the marketplace comes from South America, international locations like Brazil, Argentina, or Colombia, or locations like New Zealand the place cattle can roam on pasture year-round. Properly-managed grazing can assist ecosystems, enhance soil well being, and sequester carbon. So there’s a possible environmental profit when collagen is grass-fed and sustainably raised versus coming from industrial feedlot operations. So I believe selecting a grass-fed choice of collagen is important.
However right here is the actually important level. That’s simpler mentioned than achieved relating to collagen dietary supplements as a result of there isn’t any authorized definition of the time period “grass-fed” in dietary supplements. It’s fully unregulated. Dietary dietary supplements, together with collagen powders or capsules, are regulated by the FDA as a class of meals, however “grass-fed” shouldn’t be a legally outlined time period below FDA rules. Not like phrases like “natural,” which have strict USDA definitions and certification, “grass-fed” is a voluntary advertising and marketing declare. There isn’t any particular federal regulation or binding FDA rule that dictates what “grass-fed” should imply on a complement label. In apply, which means when a collagen is marketed as grass-fed, it’s largely as much as the producer to make sure that the declare is truthful.
Authorities oversight is proscribed to normal truth-in-advertising rules. The FTC prohibits deceptive or false labels on merchandise, and the FDA can take motion if a label is blatantly misleading. However there’s no pre-approval or standardized definition for “grass-fed” on dietary supplements the best way there may be for sure nutrient content material or well being claims. Put extra merely, any complement firm can say their collagen is grass-fed, and you don’t have any method of understanding if that’s true. In truth, many complement corporations don’t even know themselves if it’s true. They may ask their contract producer to supply a grass-fed collagen ingredient, and the ingredient provider tells the producer their collagen is grass-fed. However what does that really imply? Did the cows get publicity to grass for his or her complete life? Or was it just some months? Or perhaps a number of days? There’s no method the producer or complement model can know as a result of the availability chain isn’t absolutely clear or traceable within the overwhelming majority of circumstances.
That is why certification is totally important relating to grass-fed collagen. The American Grassfed Affiliation units requirements for actually grass-fed animal merchandise. For a collagen to be licensed grass-fed, it means the cattle spent 100%, not 50 %, not 70 %, not 90 %, [but] 100% of their lives on pasture, consuming a pure forage food regimen with no confinement for feeding or feedlot grain ending. It additionally means no hormones or antibiotics have been used. This can be a excessive bar to satisfy.
Like what you’re studying? Get my free publication, recipes, eBooks, product suggestions, and extra!
As of now, there is just one collagen ingredient I’m conscious of that has achieved this. It’s known as SOLUGEL® licensed grass-fed collagen. This isn’t a model of collagen you could purchase. That is an ingredient that complement manufacturers can use to make their collagen product. SOLUGEL® is an ingredient made by an organization known as PB Liner. This can be a very respected firm within the complement ingredient house and so they labored with a 3rd get together certifier known as LIAF Management in collaboration with the American Grassfed Affiliation to certify their collagen peptides as grass-fed. Their cattle are raised in Latin America on household ranches and oftentimes these ranches have been in households for a number of generations. The cattle free-roam outside consuming grass for his or her complete life, and so they’re by no means confined or given development hormones. The result’s a collagen peptide product that may carry the “AGA Licensed Grassfed” seal. And once more, it’s at present the one bovine collagen on the earth that I’m conscious of on the time of this recording to have that 100% grass-fed certification. That’s an enormous deal in the event you care in regards to the authenticity of the grass-fed declare.
So why may you select a product with SOLUGEL® grass-fed collagen? Other than the animal welfare and moral elements, you recognize you’re getting a pure and clear product. It’s free from hormones, antibiotics, and steroids, and it has a very traceable provide chain. They know which farms the hides come from, and so they have protocols in place to make sure high quality at each step, from the pasture to the processing facility. For individuals like myself, and I think about lots of you listening to this present, who’re involved about the place their meals and dietary supplements come from, that transparency and assurance are actually helpful.
Environmentally, utilizing hides from grass-fed operations helps these farms and ranches who’re elevating animals in a extra sustainable method. It’s like voting along with your greenback. You’re saying you assist regenerative agriculture. Many grass-fed cattle, particularly in locations like Brazil or Argentina, are raised on land that’s been grassland for hundreds of years. Ideally, if collagen demand can incentivize preserving land as pasture moderately than plowing it for monocrops, that may be web constructive ecologically. Now, I need to observe right here that non-grass-fed collagen isn’t inherently unhealthy. Quite a lot of collagen comes from mixed-feed cattle, and people merchandise can nonetheless be top quality by way of purity and amino acid profile. In addition they typically supply from hides that may be wasted in any other case, so it’s nonetheless a recycling of sources. However if in case you have the choice and if it suits your finances, grass-fed is a extremely important improve. I must also point out that not all merchandise that declare to be grass-fed should not absolutely grass-fed. The issue is that you simply simply don’t know, as a result of there’s no certification course of in place and there’s not a completely clear provide chain as there may be with the SOLUGEL® licensed grass-fed collagen peptides. I must also point out that the SOLUGEL® ingredient has a low molecular weight, with a mean peptide dimension of two kilodaltons or 2,000 daltons. As I discussed earlier, that is essential as a result of the collagen peptides shall be extra bioavailable and efficient, simpler to combine with water and different liquids, and fewer prone to trigger digestive points.
Yet one more fast observe, there are additionally marine collagens for many who don’t need bovine or porcine sources for dietary or spiritual causes. Should you do go the marine route, search for wild-caught fish sources and testing for issues like heavy metals as a result of fish collagen typically comes from fish pores and skin and scales, usually of cod or snapper, and people species can include important mercury ranges. Marine collagen is often sort I and could be a bit dearer gram-for-gram than bovine, but it surely’s an choice in the event you’re allergic to beef or don’t need to eat beef or porcine collagen sources.
Now that we’ve lined high quality and sourcing, let’s handle a number of closing factors of warning and make clear any issues when utilizing collagen. The excellent news is collagen is a really protected complement for most individuals. In any case, it’s mainly a meals. However as with something, there are some things to bear in mind earlier than you soar on the collagen practice.
Cautions and Concerns
Let’s go over some potential issues and the way collagen differs from different protein dietary supplements and be sure that we keep a balanced perspective right here. Collagen has a superb security profile in research. Analysis trials, even at pretty excessive doses, present that the prevalence of negative effects is not any totally different than placebo. This is smart – our physique naturally metabolizes collagen peptides as it could another protein, and so they don’t are inclined to trigger GI misery in most individuals, with the exception, as I discussed, of people that have GI points. Generally [they] don’t course of bigger quantities like 10 grams of collagen effectively, in order that’s why it’s essential to decide on a product with a low molecular weight peptides. Collagen isn’t a stimulant as we mentioned, so that they gained’t trigger jitters or insomnia. Reasonably, the other, as we mentioned with glycine. About the one minor aspect impact that’s often reported is a sense of fullness. However once more, that may be averted with selecting a product with low molecular weight peptides.
One essential consideration is allergic reactions. If in case you have an allergy to beef or pork or fish, clearly you need to keep away from that as a supply of collagen. Beef allergy shouldn’t be frequent, however there’s something known as alpha-gal syndrome from a tick chunk that causes pink meat allergy that’s been growing in prevalence recently. However if in case you have that, you most likely already know who you might be and you’ll keep away from beef collagen. Collagen is a protein, so if in case you have any medical situation the place protein consumption is restricted, like superior kidney illness, you would want to rely collagen towards your whole protein consumption and seek the advice of along with your healthcare supplier. Keep in mind that collagen shouldn’t be an entire protein. It’s low in a few of the important amino acids like leucine and tryptophan that are essential for muscle protein synthesis, so that you shouldn’t use collagen as your sole protein supply. I believe that may be not possible for somebody to do, however I simply need to name that out right here.
When desirous about collagen versus gelatin versus bone broth, know that gelatin is simply collagen that’s been partially damaged down. It gels in deserts. Bone broth is a whole-food supply containing gelatin plus minerals. Should you’re consuming bone broth frequently and consuming nose-to-tail, you won’t want a collagen complement on prime of that. However once more, these collagen proteins in gelatin should not as damaged down as they’d be in a high-quality, low molecular weight collagen complement. So many individuals select to make use of each, together with myself. I exploit broth in cooking fairly a bit. I’ll typically simply drink bone broth. It’s a daily a part of my food regimen. I eat nose-to-tail. I do take pleasure in steak, however I additionally eat different cuts of meat. For instance, final evening we had a slow-cooked brisket. You may have chuck roast, stew, oxtail, ribs, and so forth. You’re going to get gelatin and collagen that method. However I additionally take collagen peptides frequently, and I believe that’s the very best method for most individuals. When it comes to price, collagen isn’t essentially the most cost effective complement, however when you think about that it mainly may very well be changing or augmenting a few of your meals and protein finances, I believe it’s affordable, and particularly given the depth and breadth of the well being advantages which can be related to collagen.
Yet one more key differentiation I need to make right here is between collagen itself and vitamins that assist collagen manufacturing. Vitamins like vitamin C, copper, zinc, and silica are essential for collagen manufacturing. They’re crucial for our physique to supply collagen by itself. Nonetheless, research have proven that taking these vitamins doesn’t have the identical affect as taking collagen itself. The advantages that we’ve mentioned on this podcast have been from taking collagen, not taking the vitamins that assist collagen manufacturing. And this admittedly creates a bit of little bit of a problem for vegetarians and vegans, as a result of all collagen sources are of animal origin, whether or not you’re speaking about bovine supply, porcine, or fish supply. All of them come from animals. So if you’re a vegetarian or vegan, your solely choice at this level is to take these vitamins like vitamin C, copper, zinc, and silica. There are some corporations now which can be doing recombinant DNA sources of human collagen. I believe there’s nonetheless some points to be labored on the market and security questions and issues and so they’re not broadly obtainable in the marketplace but. That is perhaps a route sooner or later that is smart, however for now I believe most vegans and vegetarians are going to be higher off simply taking these collagen-supportive vitamins.
We’ve lined loads of floor right now on collagen. Thanks for sticking with me. We’ve talked about what it’s, why it’s essential, [and] the way it can profit numerous elements of your well being. I hope this dialogue has demystified collagen for you. It’s an exquisite instance of a useful meals, one thing that blurs the road between diet and medication, serving to to deal with root causes like rebuilding tissues moderately than simply masking signs. It aligns with what I typically emphasize, [which is] a holistic method to well being that’s sensible and primarily based on our evolutionary wants. Should you’re desirous about making an attempt collagen, you now know what to search for and how one can use it. It may very well be a easy addition to your morning routine or night wind-down (or each) that yields delicate however significant enhancements in the way you look, really feel, and transfer.
Personally, collagen has turn out to be a staple in my each day routine and I’ve seen its advantages in each my very own well being and in lots of my sufferers and listeners through the years. As at all times, I encourage you to concentrate to your individual physique. Some individuals might discover an enormous distinction with collagen proper off the bat. Others perhaps much less so. However once more, you could give it a minimum of that three-month interval to totally consider its results. And in the event you’re taking it for bone well being, these advantages will proceed to build up for a 12 months or extra.
So thanks for becoming a member of me right now on this deep dive on collagen. It’s been a pleasure to share this with you. I hope you discover it useful and that it empowers you to make knowledgeable choices about your well being. Bear in mind, small steps like including nutrient-dense meals or dietary supplements can add as much as important enhancements over time. Thanks for listening and see you subsequent time.